Bone Healthy Living / Experts / Research / Video / November 23, 2011

Scientists at the Canada’s Intitut De Recherches Cliniques De Montreal have discovered a gene that they believe has controlling influence on bone mass of an individual thus proving critical to predisposing a person to osteoporosis. (1) The study was funded by the Canadian Institutes of Health Research (CIHR) and the Natural Sciences and Engineering Research Council of Canada (NSERC) and it’s findings were published in the October issue of Cell Metabolism. The research team was trying to find out about the mechanisms that were involved in bone formation and bone mineral dissolution causing bone breakdown. Bone formation was brought on by the production of bone cells called osteoblasts. Dissolution of bone known as resorption of bone was caused by the manufacture of bone cells called osteoclasts. These two types of bone cells work in tandem which reshapes the bones and…

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Bone Healthy Living / Research / November 16, 2011

Stem cells are biological cells that may develop into many different types of cells in the body in its early stages of development. They are known to serve as a sort of internal repair system, dividing without limit to replenish other cells as and when required.(1) Now a study conducted by the National Institute of Standards and Technology shows that it is possible to ‘induce’ stem cells to develop into a certain specific type of cell just by controlling their shape. This has immensely beneficial implications in the field of osteoporosis treatment as it points at designing material which will help regeneration of lost or damaged tissues in the body.(2) It is known that in the realms of tissue-engineering, the primary objective is to repair as well as regenerate partially lost or damaged body tissues. This is done using stem…

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Bone Healthy Living / Other / Research / Video / November 16, 2011

We have known for some time that aging causes our bones to become brittle and in turn makes them more susceptible to fractures. So far the reason attributed to brittleness of bones was the loss of mass or quantity of bone in the senior population. Because of this reason the focus of most bone-health research was to come up with solutions to retard if not reduce this quantity of bone loss. However, scientists from the Lawrence Berkeley National Laboratory (U.S Department of Energy) have come up with some very interesting findings from their new research (supported by a grant from the National Institutes of Health). They say that it is not only the loss in the quantity or mass of bone but also in the quality of bone that occur at the microscopic level which is as responsible for the…

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Bone Healthy Living / Research / November 10, 2011

It’s not your imagination that kids are breaking more bones now than their parents did. A Mayo Clinic study published in JAMA discovered that forearm fractures have risen more than 32% in boys, and 56% in girls in the past 30 years. The Mayo clinic study also found a correlation between forearm fractures and an increased risk of hip fractures and osteoporosis later in life. Focusing on kids’ bone health now, can have immediate and far-reaching benefits. Getting the right nutrients for bones is important for kids, because peak bone mass is reached before the age of 25, according to The International Osteoporosis Foundation. A number of different dietary and lifestyle factors could be linked to the rise in fractures and causing kids to not maximize their bone growth: Mineral depletion of our soil & food processing = mineral depleted…

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Bone Healthy Living / Research / November 9, 2011

Osteoporosis therapy has got a shot in the arm with the new study conducted by the researchers at Mount Sinai School of Medicine which reveals that thyroid stimulating hormone (TSH) encourages bone growth. This could be a vital finding that could help osteoporosis treatments especially such of the cases that involve bone cancer-induced bone loss. The thyroid stimulating hormone is actually produced by the anterior part of the pituitary gland, which is a pea-sized organ located in the hypothalamus at the base of the brain responsible for the growth of the thyroid gland in the neck, stimulating it to produce more thyroid hormones. (1) However, the study, findings of which were published in the Proceedings of the National Academy of Sciences, has now noted that the thyroid stimulating hormone can promote bone growth independent of it’s core thyroid functions. The…

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Bone Healthy Living / Nutrition / October 14, 2011

Reclast is a Novartis drug from the bisphosphonate family (chemical name: zoledronic acid or zoledronate) that prevents the release of calcium from bones, thus reducing the rate of bone mass deterioration, especially in post-menopausal women. The chemical is also sold under the brand name Zometa. It is prescribed for men to help increase their bone mass and is especially recommended in persons who will be on any steroid combination for over a year as a part of their osteoporosis management program. (1) Now there is sufficient evidence that Reclast raises the risk for kidney failure in osteoporosis patients especially if they already have kidney impairment or suffer from severe dehydration. The U.S Food and Drug Administration (FDA) has gone further to warn such patients as those on potentially kidney-damaging medications or diuretics while they are being given Reclast. Though the…

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Bone Healthy Living / Research / October 14, 2011

There is now evidence through studies that a complete removal or radical surgery of the kidney points at the increased possibility of bone brittleness later at life, especially for women in their senior years. Researchers from the San Diego School of Medicine, University of California are now suggesting that it is important for doctors to evaluate the possibility of pursuing a kidney-sparing surgery in an effort to preserve kidney function and to reduce the risk of bone fractures later in life including the risk of developing osteoporosis. (1) It is believed that though radical nephrectomy (surgery of the kidneys) is an easier procedure to perform, it is loaded with more complications in the post-operative phase, such as metabolic complications including metabolic acidosis, muscle wasting, osteoporosis, cardiovascular disease, and death. (2) Carcinoma of kidney cells is a commonly diagnosed urological malignancy…

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Bone Healthy Living / Treatment / October 14, 2011

Though osteoporosis has always been associated more with women than men and media content on osteoporosis usually covers women because they are more susceptible to the condition, a quiet 17 million men over the age of 50 go unspoken about. (1) However, there is hope in the form of a new risk assessment tool developed by the World Health Organization called the FRAX® tool that helps detect the level of risk of osteoporosis in both men and women. Dr. Silvina Levis, Founder and Director of Osteoporosis Center (a clinical research center and a joint venture Miller School of Medicine and the Miami VA Medical Center), even goes on to point that once men get a fracture of the hips due to osteoporosis, their chances of dying after the incident doubles when compared to women. The FRAX tool will ask the…

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